node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AJR06685.1 | AJR07231.1 | H744_1c1667 | H744_2c0495 | Putative L-serine dehydratase 1; COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine acetyltransferase; COG1045. | 0.918 |
AJR06685.1 | AJR07358.1 | H744_1c1667 | H744_2c0627 | Putative L-serine dehydratase 1; COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Putative Serine-pyruvate aminotransferase/ aspartate aminotransferase; COG0075. | 0.905 |
AJR06685.1 | AJR08124.1 | H744_1c1667 | H744_2c1446 | Putative L-serine dehydratase 1; COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Putative L-serine dehydratase 1; COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.903 |
AJR06685.1 | AJR09102.1 | H744_1c1667 | H744_2c2446 | Putative L-serine dehydratase 1; COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Hypothetical protein; COG3616. | 0.901 |
AJR06685.1 | AJR09801.1 | H744_1c1667 | H744_2c3157 | Putative L-serine dehydratase 1; COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Phosphoserine phosphatase; COG0560,COG3830. | 0.914 |
AJR06685.1 | glyA | H744_1c1667 | H744_1c0724 | Putative L-serine dehydratase 1; COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.950 |
AJR06685.1 | glyA-2 | H744_1c1667 | H744_2c3036 | Putative L-serine dehydratase 1; COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.950 |
AJR06685.1 | ilvA | H744_1c1667 | H744_2c0292 | Putative L-serine dehydratase 1; COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.926 |
AJR06685.1 | trpA | H744_1c1667 | H744_2c2717 | Putative L-serine dehydratase 1; COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.904 |
AJR06685.1 | trpB | H744_1c1667 | H744_1c1382 | Putative L-serine dehydratase 1; COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
AJR07231.1 | AJR06685.1 | H744_2c0495 | H744_1c1667 | Serine acetyltransferase; COG1045. | Putative L-serine dehydratase 1; COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.918 |
AJR07231.1 | AJR07358.1 | H744_2c0495 | H744_2c0627 | Serine acetyltransferase; COG1045. | Putative Serine-pyruvate aminotransferase/ aspartate aminotransferase; COG0075. | 0.800 |
AJR07231.1 | AJR08124.1 | H744_2c0495 | H744_2c1446 | Serine acetyltransferase; COG1045. | Putative L-serine dehydratase 1; COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.918 |
AJR07231.1 | AJR09801.1 | H744_2c0495 | H744_2c3157 | Serine acetyltransferase; COG1045. | Phosphoserine phosphatase; COG0560,COG3830. | 0.856 |
AJR07231.1 | glyA | H744_2c0495 | H744_1c0724 | Serine acetyltransferase; COG1045. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.840 |
AJR07231.1 | glyA-2 | H744_2c0495 | H744_2c3036 | Serine acetyltransferase; COG1045. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.840 |
AJR07231.1 | ilvA | H744_2c0495 | H744_2c0292 | Serine acetyltransferase; COG1045. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.816 |
AJR07231.1 | trpA | H744_2c0495 | H744_2c2717 | Serine acetyltransferase; COG1045. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.824 |
AJR07231.1 | trpB | H744_2c0495 | H744_1c1382 | Serine acetyltransferase; COG1045. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.812 |
AJR07358.1 | AJR06685.1 | H744_2c0627 | H744_1c1667 | Putative Serine-pyruvate aminotransferase/ aspartate aminotransferase; COG0075. | Putative L-serine dehydratase 1; COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.905 |