STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metJTranscriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. (105 aa)    
Predicted Functional Partners:
AJR07257.1
Bifunctional aspartate kinase II/homoserine dehydrogenase II; COG0460,COG0527; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
  
 0.854
seqA
Replication initiation regulator SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
    0.809
AJR07258.1
5,10-methylenetetrahydrofolate reductase; COG0685; Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.798
rraB
Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.773
AJR09818.1
Lipoprotein NlpI; May be involved in cell division.
  
     0.768
fadR
Fatty acid metabolism regulator; Multifunctional regulator of fatty acid metabolism.
  
   
 0.763
proQ
Putative solute/DNA competence effector; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family.
  
     0.762
AJR06925.1
DNA-binding transcriptional repressor FabR; COG1309.
  
   
 0.759
mutH
DNA mismatch repair protein; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.
  
     0.758
AJR07760.1
Hypothetical protein; COG3092.
  
     0.748
Your Current Organism:
Photobacterium gaetbulicola
NCBI taxonomy Id: 658445
Other names: P. gaetbulicola Gung47, Photobacterium gaetbulicola Gung47, Photobacterium sp. Gung47
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