| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJR07064.1 | AJR07486.1 | H744_2c0320 | H744_2c0764 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.670 |
| AJR07064.1 | AJR07832.1 | H744_2c0320 | H744_2c1145 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exonuclease III; COG0708. | 0.906 |
| AJR07064.1 | mutS | H744_2c0320 | H744_2c0835 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.980 |
| AJR07485.1 | AJR07486.1 | H744_2c0763 | H744_2c0764 | Hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.590 |
| AJR07485.1 | trmB | H744_2c0763 | H744_2c0765 | Hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.434 |
| AJR07486.1 | AJR07064.1 | H744_2c0764 | H744_2c0320 | Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.670 |
| AJR07486.1 | AJR07485.1 | H744_2c0764 | H744_2c0763 | Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.590 |
| AJR07486.1 | AJR07490.1 | H744_2c0764 | H744_2c0768 | Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.527 |
| AJR07486.1 | AJR07832.1 | H744_2c0764 | H744_2c1145 | Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Exonuclease III; COG0708. | 0.894 |
| AJR07486.1 | birA | H744_2c0764 | H744_2c0155 | Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.529 |
| AJR07486.1 | glsA | H744_2c0764 | H744_2c0766 | Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Glutaminase; COG2066; Belongs to the glutaminase family. | 0.449 |
| AJR07486.1 | mutS | H744_2c0764 | H744_2c0835 | Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.516 |
| AJR07486.1 | sfsA | H744_2c0764 | H744_2c0748 | Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Sugar fermentation stimulation protein A; COG1489; Belongs to the SfsA family. | 0.668 |
| AJR07486.1 | trmB | H744_2c0764 | H744_2c0765 | Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.626 |
| AJR07486.1 | trpF | H744_2c0764 | H744_2c2715 | Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; COG0134,COG0135; Belongs to the TrpC family. | 0.489 |
| AJR07490.1 | AJR07486.1 | H744_2c0768 | H744_2c0764 | Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.527 |
| AJR07832.1 | AJR07064.1 | H744_2c1145 | H744_2c0320 | Exonuclease III; COG0708. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.906 |
| AJR07832.1 | AJR07486.1 | H744_2c1145 | H744_2c0764 | Exonuclease III; COG0708. | Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.894 |
| AJR07832.1 | birA | H744_2c1145 | H744_2c0155 | Exonuclease III; COG0708. | Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.877 |
| birA | AJR07486.1 | H744_2c0155 | H744_2c0764 | Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.529 |