node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AJR05766.1 | AJR06711.1 | H744_1c0741 | H744_1c1693 | Putative threonine aldolase; COG2008. | Amidinotransferase family protein; COG1834. | 0.904 |
AJR05766.1 | AJR07358.1 | H744_1c0741 | H744_2c0627 | Putative threonine aldolase; COG2008. | Putative Serine-pyruvate aminotransferase/ aspartate aminotransferase; COG0075. | 0.919 |
AJR05766.1 | gcvP | H744_1c0741 | H744_1c0722 | Putative threonine aldolase; COG2008. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.942 |
AJR05766.1 | glyA | H744_1c0741 | H744_1c0724 | Putative threonine aldolase; COG2008. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.927 |
AJR05766.1 | glyA-2 | H744_1c0741 | H744_2c3036 | Putative threonine aldolase; COG2008. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.927 |
AJR05766.1 | kbl | H744_1c0741 | H744_2c2216 | Putative threonine aldolase; COG2008. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.920 |
AJR05766.1 | tdh | H744_1c0741 | H744_2c2215 | Putative threonine aldolase; COG2008. | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.902 |
AJR06711.1 | AJR05766.1 | H744_1c1693 | H744_1c0741 | Amidinotransferase family protein; COG1834. | Putative threonine aldolase; COG2008. | 0.904 |
AJR06711.1 | AJR07358.1 | H744_1c1693 | H744_2c0627 | Amidinotransferase family protein; COG1834. | Putative Serine-pyruvate aminotransferase/ aspartate aminotransferase; COG0075. | 0.900 |
AJR06711.1 | gcvP | H744_1c1693 | H744_1c0722 | Amidinotransferase family protein; COG1834. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.900 |
AJR06711.1 | glyA | H744_1c1693 | H744_1c0724 | Amidinotransferase family protein; COG1834. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.900 |
AJR06711.1 | glyA-2 | H744_1c1693 | H744_2c3036 | Amidinotransferase family protein; COG1834. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.900 |
AJR06711.1 | kbl | H744_1c1693 | H744_2c2216 | Amidinotransferase family protein; COG1834. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.900 |
AJR07358.1 | AJR05766.1 | H744_2c0627 | H744_1c0741 | Putative Serine-pyruvate aminotransferase/ aspartate aminotransferase; COG0075. | Putative threonine aldolase; COG2008. | 0.919 |
AJR07358.1 | AJR06711.1 | H744_2c0627 | H744_1c1693 | Putative Serine-pyruvate aminotransferase/ aspartate aminotransferase; COG0075. | Amidinotransferase family protein; COG1834. | 0.900 |
AJR07358.1 | gcvP | H744_2c0627 | H744_1c0722 | Putative Serine-pyruvate aminotransferase/ aspartate aminotransferase; COG0075. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.925 |
AJR07358.1 | glyA | H744_2c0627 | H744_1c0724 | Putative Serine-pyruvate aminotransferase/ aspartate aminotransferase; COG0075. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.916 |
AJR07358.1 | glyA-2 | H744_2c0627 | H744_2c3036 | Putative Serine-pyruvate aminotransferase/ aspartate aminotransferase; COG0075. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.916 |
AJR07358.1 | kbl | H744_2c0627 | H744_2c2216 | Putative Serine-pyruvate aminotransferase/ aspartate aminotransferase; COG0075. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.906 |
bioB | bioC | H744_2c1527 | H744_2c1529 | Putative biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Putative biotin synthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.960 |