STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recURecombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. (183 aa)    
Predicted Functional Partners:
EGN33662.1
Hypothetical protein; Belongs to the pseudouridine synthase RluA family.
 
     0.844
EGN31117.1
Hypothetical protein.
  
     0.717
EGN38225.1
Hypothetical protein.
  
     0.715
hisZ
Hypothetical protein; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
       0.705
EGN33659.1
Hypothetical protein.
       0.683
EGN33658.1
Hypothetical protein; Belongs to the pseudouridine synthase RsuA family.
  
    0.680
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
       0.639
EGN33665.1
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
       0.637
EGN33666.1
Hypothetical protein.
       0.637
EGN33661.1
Hypothetical protein.
       0.626
Your Current Organism:
Lachnospiraceae bacterium 1456FAA
NCBI taxonomy Id: 658655
Other names: L. bacterium 1_4_56FAA, Lachnospiraceae bacterium 1_4_56FAA
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.