Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EGC75901.1Hypothetical protein; Belongs to the pseudouridine synthase RsuA family. (237 aa)    
Predicted Functional Partners:
EGC76246.1
Exodeoxyribonuclease.
  
    0.914
EGC75900.1
Hypothetical protein.
     
 0.851
EGC75902.1
Hypothetical protein.
       0.821
cmk
Cytidylate kinase.
 
  
 0.755
der
GTP-binding protein engA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.709
EGC75903.1
Hypothetical protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.681
EGC75905.1
Hypothetical protein; Belongs to the pseudouridine synthase RluA family.
  
 
 0.653
EGC75904.1
Hypothetical protein.
       0.634
EGC74390.1
Hypothetical protein.
      0.613
recU
Hypothetical protein; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
  
    0.588
Your Current Organism:
Lachnospiraceae bacterium 6137FAA
NCBI taxonomy Id: 658656
Other names: L. bacterium 6_1_37FAA, Lachnospiraceae bacterium 6_1_37FAA
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