| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EGC74068.1 | EGC74780.1 | HMPREF0490_02575 | HMPREF0490_01467 | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | ATP-dependent DNA helicase PcrA. | 0.896 |
| EGC74068.1 | EGC74996.1 | HMPREF0490_02575 | HMPREF0490_01284 | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | Hypothetical protein. | 0.918 |
| EGC74068.1 | EGC75030.1 | HMPREF0490_02575 | HMPREF0490_01192 | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | Hypothetical protein. | 0.898 |
| EGC74068.1 | EGC75767.1 | HMPREF0490_02575 | HMPREF0490_00409 | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | Hypothetical protein. | 0.860 |
| EGC74068.1 | EGC75768.1 | HMPREF0490_02575 | HMPREF0490_00410 | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | Hypothetical protein. | 0.852 |
| EGC74068.1 | EGC76070.1 | HMPREF0490_02575 | HMPREF0490_00146 | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | ATP-dependent DNA helicase RecQ. | 0.898 |
| EGC74068.1 | mutL | HMPREF0490_02575 | HMPREF0490_00965 | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | Hypothetical protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.970 |
| EGC74068.1 | mutS | HMPREF0490_02575 | HMPREF0490_00966 | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | DNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.932 |
| EGC74068.1 | polA | HMPREF0490_02575 | HMPREF0490_00607 | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | Hypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.995 |
| EGC74780.1 | EGC74068.1 | HMPREF0490_01467 | HMPREF0490_02575 | ATP-dependent DNA helicase PcrA. | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | 0.896 |
| EGC74780.1 | EGC75030.1 | HMPREF0490_01467 | HMPREF0490_01192 | ATP-dependent DNA helicase PcrA. | Hypothetical protein. | 0.870 |
| EGC74780.1 | EGC75767.1 | HMPREF0490_01467 | HMPREF0490_00409 | ATP-dependent DNA helicase PcrA. | Hypothetical protein. | 0.865 |
| EGC74780.1 | EGC75768.1 | HMPREF0490_01467 | HMPREF0490_00410 | ATP-dependent DNA helicase PcrA. | Hypothetical protein. | 0.872 |
| EGC74780.1 | EGC76070.1 | HMPREF0490_01467 | HMPREF0490_00146 | ATP-dependent DNA helicase PcrA. | ATP-dependent DNA helicase RecQ. | 0.913 |
| EGC74780.1 | mutL | HMPREF0490_01467 | HMPREF0490_00965 | ATP-dependent DNA helicase PcrA. | Hypothetical protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.890 |
| EGC74780.1 | polA | HMPREF0490_01467 | HMPREF0490_00607 | ATP-dependent DNA helicase PcrA. | Hypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.721 |
| EGC74996.1 | EGC74068.1 | HMPREF0490_01284 | HMPREF0490_02575 | Hypothetical protein. | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | 0.918 |
| EGC74996.1 | EGC75030.1 | HMPREF0490_01284 | HMPREF0490_01192 | Hypothetical protein. | Hypothetical protein. | 0.570 |
| EGC74996.1 | EGC76070.1 | HMPREF0490_01284 | HMPREF0490_00146 | Hypothetical protein. | ATP-dependent DNA helicase RecQ. | 0.624 |
| EGC74996.1 | mutL | HMPREF0490_01284 | HMPREF0490_00965 | Hypothetical protein. | Hypothetical protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.978 |
