Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EGC74892.1Hypothetical protein. (564 aa)    
Predicted Functional Partners:
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 0.957
cmk
Cytidylate kinase.
   
 
 0.834
EGC73909.1
Ribose 5-phosphate isomerase B.
  
  0.833
EGC76262.1
Hypothetical protein.
    
 0.823
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.819
EGC76267.1
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
    
 0.811
EGC75223.1
Hypothetical protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
  0.807
pyrF
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.796
EGC73952.1
Hypothetical protein; Belongs to the DEAD box helicase family.
  
  0.795
EGC75942.1
Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.782
Your Current Organism:
Lachnospiraceae bacterium 6137FAA
NCBI taxonomy Id: 658656
Other names: L. bacterium 6_1_37FAA, Lachnospiraceae bacterium 6_1_37FAA
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