Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EGC74687.1Hypothetical protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (212 aa)    
Predicted Functional Partners:
EGC74148.1
Hypothetical protein.
   
  0.900
EGC74918.1
Redox-active disulfide protein 2.
    
 0.874
EGC74742.1
Hypothetical protein.
  
 0.866
EGC74724.1
Hypothetical protein.
   
 0.863
EGC73952.1
Hypothetical protein; Belongs to the DEAD box helicase family.
 
 0.862
dnaK
Chaperone dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.837
EGC75725.1
Hypothetical protein; Belongs to the heat shock protein 70 family.
 
 0.826
EGC75161.1
Hypothetical protein.
  
  0.818
rplD
50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
  
 0.763
dnaJ
Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...]
 
  0.753
Your Current Organism:
Lachnospiraceae bacterium 6137FAA
NCBI taxonomy Id: 658656
Other names: L. bacterium 6_1_37FAA, Lachnospiraceae bacterium 6_1_37FAA
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