Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EGC74533.1Hypothetical protein. (250 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.858
EGC74534.1
Hypothetical protein.
 
     0.853
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
  0.845
EGC74532.1
Hypothetical protein.
 
     0.809
EGC74535.1
Hypothetical protein.
 
    0.730
EGC73542.1
Hypothetical protein.
    
   0.723
EGC75713.1
Hypothetical protein; Belongs to the CinA family.
  
 
  0.564
nadD
Nicotinate nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 
  0.518
EGC74389.1
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
  
  0.508
EGC75832.1
Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
  
 
 0.486
Your Current Organism:
Lachnospiraceae bacterium 6137FAA
NCBI taxonomy Id: 658656
Other names: L. bacterium 6_1_37FAA, Lachnospiraceae bacterium 6_1_37FAA
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