| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EGC73689.1 | EGC74063.1 | HMPREF0490_02710 | HMPREF0490_02570 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Hypothetical protein. | 0.956 |
| EGC73689.1 | EGC74356.1 | HMPREF0490_02710 | HMPREF0490_01973 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Hypothetical protein; Belongs to the SecE/SEC61-gamma family. | 0.995 |
| EGC73689.1 | ftsY | HMPREF0490_02710 | HMPREF0490_00629 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.957 |
| EGC73689.1 | nusG | HMPREF0490_02710 | HMPREF0490_01972 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | 0.554 |
| EGC73689.1 | rplA | HMPREF0490_02710 | HMPREF0490_01970 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.760 |
| EGC73689.1 | rplK | HMPREF0490_02710 | HMPREF0490_01971 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.695 |
| EGC73689.1 | rpmG | HMPREF0490_02710 | HMPREF0490_01974 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. | 0.709 |
| EGC73689.1 | secA | HMPREF0490_02710 | HMPREF0490_01785 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.980 |
| EGC73689.1 | secD | HMPREF0490_02710 | HMPREF0490_01681 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Hypothetical protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.972 |
| EGC73689.1 | secY | HMPREF0490_02710 | HMPREF0490_02232 | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.989 |
| EGC74063.1 | EGC73689.1 | HMPREF0490_02570 | HMPREF0490_02710 | Hypothetical protein. | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.956 |
| EGC74063.1 | EGC74356.1 | HMPREF0490_02570 | HMPREF0490_01973 | Hypothetical protein. | Hypothetical protein; Belongs to the SecE/SEC61-gamma family. | 0.985 |
| EGC74063.1 | ftsY | HMPREF0490_02570 | HMPREF0490_00629 | Hypothetical protein. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.920 |
| EGC74063.1 | rplA | HMPREF0490_02570 | HMPREF0490_01970 | Hypothetical protein. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.415 |
| EGC74063.1 | rplK | HMPREF0490_02570 | HMPREF0490_01971 | Hypothetical protein. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.427 |
| EGC74063.1 | rpmG | HMPREF0490_02570 | HMPREF0490_01974 | Hypothetical protein. | 50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. | 0.809 |
| EGC74063.1 | secA | HMPREF0490_02570 | HMPREF0490_01785 | Hypothetical protein. | Translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.936 |
| EGC74063.1 | secD | HMPREF0490_02570 | HMPREF0490_01681 | Hypothetical protein. | Hypothetical protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.998 |
| EGC74063.1 | secY | HMPREF0490_02570 | HMPREF0490_02232 | Hypothetical protein. | Preprotein translocase; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.985 |
| EGC74356.1 | EGC73689.1 | HMPREF0490_01973 | HMPREF0490_02710 | Hypothetical protein; Belongs to the SecE/SEC61-gamma family. | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.995 |
