STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1CRISPR-associated protein cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (332 aa)    
Predicted Functional Partners:
cas2
CRISPR-associated protein cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.999
EGC74254.1
CRISPR-associated protein cas4.
 
 
 
 0.992
EGC74255.1
Hypothetical protein.
 
  
 0.950
EGC74256.1
CRISPR-associated protein cas5.
 
   
 0.929
EGC74260.1
Hypothetical protein.
 
   
 0.905
EGC74257.1
Hypothetical protein.
 
   
 0.898
EGC74258.1
Hypothetical protein.
 
     0.874
EGC76278.1
Hypothetical protein.
 
  
 0.722
EGC75503.1
Hypothetical protein; Belongs to the bacterial histone-like protein family.
    
   0.571
EGC73430.1
DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
    
   0.571
Your Current Organism:
Lachnospiraceae bacterium 6137FAA
NCBI taxonomy Id: 658656
Other names: L. bacterium 6_1_37FAA, Lachnospiraceae bacterium 6_1_37FAA
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.