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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGC73749.1Hypothetical protein. (260 aa)    
Predicted Functional Partners:
EGC74068.1
DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...]
   
 0.999
polA
Hypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 0.996
EGC73748.1
Hypothetical protein.
   
 0.995
EGC74171.1
Hypothetical protein.
   
  0.982
EGC76246.1
Exodeoxyribonuclease.
   
 
  0.976
EGC73751.1
Hypothetical protein.
  
 0.970
EGC75258.1
Hypothetical protein.
   
 0.967
EGC75517.1
Hypothetical protein.
   
 
 0.907
dinB
Hypothetical protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
   
 
 0.907
EGC73750.1
Hypothetical protein.
 
     0.901
Your Current Organism:
Lachnospiraceae bacterium 6137FAA
NCBI taxonomy Id: 658656
Other names: L. bacterium 6_1_37FAA, Lachnospiraceae bacterium 6_1_37FAA
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.