Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EGC73962.1Hypothetical protein. (321 aa)    
Predicted Functional Partners:
EGC74874.1
Stage IV sporulation protein A.
  
  
 0.810
EGC73961.1
Hypothetical protein.
 
   
 0.742
EGC73425.1
Hypothetical protein.
 
   
 0.728
EGC73428.1
Sporulation protein YabP.
 
   
 0.713
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.692
EGC75167.1
Hypothetical protein.
  
  
 0.652
EGC76226.1
Hypothetical protein.
  
   
 0.647
EGC75405.1
Hypothetical protein.
  
   
 0.625
EGC76219.1
Hypothetical protein; Belongs to the anti-sigma-factor antagonist family.
  
   
 0.623
EGC75153.1
Stage III sporulation protein AA.
  
  
 0.607
Your Current Organism:
Lachnospiraceae bacterium 6137FAA
NCBI taxonomy Id: 658656
Other names: L. bacterium 6_1_37FAA, Lachnospiraceae bacterium 6_1_37FAA
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