Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (166 aa)    
Predicted Functional Partners:
purC
Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family.
 
 0.999
purD
Phosphoribosylamine--glycine ligase; Belongs to the GARS family.
 0.999
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
 
 
 0.997
EFP62487.1
Hypothetical protein; Adenylosuccinate lyase (Adenylosuccinase) (ASL) (ASASE); overlaps another CDS with the same product name.
  
 0.992
EFP62488.1
Adenylosuccinate lyase (Adenylosuccinase) (ASL) (ASASE); overlaps another CDS with the same product name.
  
 0.992
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
 
 0.989
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.
 
  
 0.984
EFP63307.1
Putative amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.972
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis.
  
 
 0.948
purA-2
Putative adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.948
Your Current Organism:
Erysipelotrichaceae bacterium 3153
NCBI taxonomy Id: 658659
Other names: E. bacterium 3_1_53, Erysipelotrichaceae bacterium 3_1_53, Erysipelotrichaceae bacterium str. 3_1_53, Erysipelotrichaceae bacterium strain 3_1_53
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