Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFP62510.1Putative SpoIVB peptidase. (336 aa)    
Predicted Functional Partners:
spo0A
Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
   
 0.906
spoVFB
Dipicolinate synthase subunit B.
  
    0.866
EFP62650.1
Sporulation initiation factor Spo0A domain protein.
   
 0.860
gpr
GPR endopeptidase.
  
    0.860
EFP60415.1
Putative sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
   
 0.841
EFP62229.1
Putative anti-sigma F factor.
 
   
 0.832
spoVAD
Stage V sporulation protein AD.
 
  
 0.817
sigF
RNA polymerase sigma-F factor; Belongs to the sigma-70 factor family.
 
   
 0.817
EFP62395.1
Putative stage V sporulation protein AC.
 
   
 0.810
sigE
RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.809
Your Current Organism:
Erysipelotrichaceae bacterium 3153
NCBI taxonomy Id: 658659
Other names: E. bacterium 3_1_53, Erysipelotrichaceae bacterium 3_1_53, Erysipelotrichaceae bacterium str. 3_1_53, Erysipelotrichaceae bacterium strain 3_1_53
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