Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFP61576.1Transcriptional regulator, PadR family. (112 aa)    
Predicted Functional Partners:
EFP61575.1
Hypothetical protein.
       0.790
EFP61574.1
ABC transporter, ATP-binding protein.
  
    0.787
EFP61573.1
Hypothetical protein.
 
     0.768
EFP62956.1
Hypothetical protein.
 
     0.749
thrC
Threonine synthase.
    
  0.594
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
    
  0.594
ilvA-2
Threonine ammonia-lyase.
    
  0.543
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
    
  0.539
EFP61572.1
Prepilin-type cleavage/methylation N-terminal domain protein.
       0.507
EFP60984.1
Hypothetical protein.
 
     0.507
Your Current Organism:
Erysipelotrichaceae bacterium 3153
NCBI taxonomy Id: 658659
Other names: E. bacterium 3_1_53, Erysipelotrichaceae bacterium 3_1_53, Erysipelotrichaceae bacterium str. 3_1_53, Erysipelotrichaceae bacterium strain 3_1_53
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.