node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KMZ52800.1 | KMZ53039.1 | HMPREF0980_03113 | HMPREF0980_02904 | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.969 |
KMZ52800.1 | KMZ55777.1 | HMPREF0980_03113 | HMPREF0980_00073 | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | Nicotinamide-nucleotide adenylyltransferase. | 0.901 |
KMZ52800.1 | KMZ55883.1 | HMPREF0980_03113 | HMPREF0980_00043 | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | Mutator MutT protein. | 0.765 |
KMZ52800.1 | cinA | HMPREF0980_03113 | HMPREF0980_01265 | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | Competence/damage-inducible protein CinA; Belongs to the CinA family. | 0.976 |
KMZ52800.1 | nadD | HMPREF0980_03113 | HMPREF0980_00959 | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.980 |
KMZ52800.1 | nadE | HMPREF0980_03113 | HMPREF0980_00568 | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | Glutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.793 |
KMZ53039.1 | KMZ52800.1 | HMPREF0980_02904 | HMPREF0980_03113 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | 0.969 |
KMZ53039.1 | KMZ53235.1 | HMPREF0980_02904 | HMPREF0980_02675 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NAD-dependent deacetylase. | 0.623 |
KMZ53039.1 | KMZ55729.1 | HMPREF0980_02904 | HMPREF0980_00428 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | SIR2 family protein. | 0.623 |
KMZ53039.1 | KMZ55777.1 | HMPREF0980_02904 | HMPREF0980_00073 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinamide-nucleotide adenylyltransferase. | 0.909 |
KMZ53039.1 | KMZ55883.1 | HMPREF0980_02904 | HMPREF0980_00043 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Mutator MutT protein. | 0.759 |
KMZ53039.1 | cinA | HMPREF0980_02904 | HMPREF0980_01265 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Competence/damage-inducible protein CinA; Belongs to the CinA family. | 0.977 |
KMZ53039.1 | cobB | HMPREF0980_02904 | HMPREF0980_02072 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.623 |
KMZ53039.1 | nadD | HMPREF0980_02904 | HMPREF0980_00959 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.989 |
KMZ53039.1 | nadE | HMPREF0980_02904 | HMPREF0980_00568 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Glutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.918 |
KMZ53039.1 | nadK | HMPREF0980_02904 | HMPREF0980_01147 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.411 |
KMZ53235.1 | KMZ53039.1 | HMPREF0980_02675 | HMPREF0980_02904 | NAD-dependent deacetylase. | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.623 |
KMZ53235.1 | KMZ55777.1 | HMPREF0980_02675 | HMPREF0980_00073 | NAD-dependent deacetylase. | Nicotinamide-nucleotide adenylyltransferase. | 0.862 |
KMZ53235.1 | KMZ55883.1 | HMPREF0980_02675 | HMPREF0980_00043 | NAD-dependent deacetylase. | Mutator MutT protein. | 0.516 |
KMZ53235.1 | cinA | HMPREF0980_02675 | HMPREF0980_01265 | NAD-dependent deacetylase. | Competence/damage-inducible protein CinA; Belongs to the CinA family. | 0.587 |