STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KMZ52682.1Hypothetical protein. (236 aa)    
Predicted Functional Partners:
KMZ54790.1
DNA gyrase, B subunit.
   
 
 0.707
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.707
KMZ53169.1
D-proline reductase, PrdA proprotein.
  
     0.665
KMZ53165.1
Hypothetical protein.
  
     0.653
KMZ53168.1
D-proline reductase, PrdA proprotein.
  
     0.647
KMZ54679.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.646
KMZ53179.1
D-proline reductase, PrdA proprotein.
  
     0.633
KMZ52967.1
Putative serine/threonine protein kinase.
 
 
 0.623
KMZ53164.1
D-proline reductase, PrdA proprotein.
  
     0.618
KMZ53180.1
D-proline reductase, PrdA proprotein.
  
     0.599
Your Current Organism:
Dorea sp. D27
NCBI taxonomy Id: 658665
Other names: D. sp. D27
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.