STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (273 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.999
KMZ52629.1
Phosphomethylpyrimidine kinase.
 
 0.999
KMZ52560.1
Thiamine-phosphate diphosphorylase.
 
 
 0.996
KMZ52556.1
Thiamine biosynthesis protein ThiS.
  
 
  0.848
KMZ52628.1
Putative phosphatase.
 
     0.830
KMZ52630.1
Putative hydroxymethylpyrimidine transporter CytX.
 
    0.820
KMZ52558.1
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
  
 0.685
KMZ53655.1
Cytosine/purine/uracil/thiamine/allantoin permease family protein; Belongs to the purine-cytosine permease (2.A.39) family.
 
    0.572
KMZ53850.1
Putative ThiH protein.
  
  
 0.560
KMZ52559.1
Thiazole biosynthesis protein ThiH.
  
  
 0.560
Your Current Organism:
Dorea sp. D27
NCBI taxonomy Id: 658665
Other names: D. sp. D27
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.