Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (236 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.996
carB
Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family.
 
  
 0.954
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.954
pyrB
Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.951
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.929
carA
Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family.
  
  
 0.927
surE
5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.903
OBU47427.1
NAD(P)H-flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.898
OBU43541.1
NAD(P)H-flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.898
udk
Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.892
Your Current Organism:
Photobacterium phosphoreum
NCBI taxonomy Id: 659
Other names: ATCC 11040, Acinetobacter phosphorescens, Bacillus hermesi, Bacillus phosphorescens II, Bacillus phosphoreus, Bacterium phosphorescens, Bacterium phosphoreum, CAIM 328, CIP 102511, Coccobacillus acropoma, DSM 15556, JCM 21184, LMG 4233, LMG:4233, Micrococcus phosphoreus, Micrococcus physiculus, NBRC 103031, P. phosphoreum, Photobacter phosphorescens, Photobacter phosphoreum, Photobacterium phosphorescens, Photobacterium profudum, Pseudomonas lucifera, Streptococcus phosphoreus
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