Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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OBU36263.1DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (463 aa)    
Predicted Functional Partners:
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.915
AYY26_07135
DEAD/DEAH box helicase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.869
OBU36286.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
   
 0.703
OBU36262.1
Pilus assembly protein PilZ; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.688
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
  
  
 0.660
thiL
Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
   
    0.642
OBU40149.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.597
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
  
   
 0.597
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.567
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
 
  
 0.563
Your Current Organism:
Photobacterium phosphoreum
NCBI taxonomy Id: 659
Other names: ATCC 11040, Acinetobacter phosphorescens, Bacillus hermesi, Bacillus phosphorescens II, Bacillus phosphoreus, Bacterium phosphorescens, Bacterium phosphoreum, CAIM 328, CIP 102511, Coccobacillus acropoma, DSM 15556, JCM 21184, LMG 4233, LMG:4233, Micrococcus phosphoreus, Micrococcus physiculus, NBRC 103031, P. phosphoreum, Photobacter phosphorescens, Photobacter phosphoreum, Photobacterium phosphorescens, Photobacterium profudum, Pseudomonas lucifera, Streptococcus phosphoreus
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