node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDE22133.1 | SDG12296.1 | SAMN04487996_10487 | SAMN04487996_115107 | Phosphoribosylanthranilate isomerase. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.767 |
SDE22133.1 | SDH07697.1 | SAMN04487996_10487 | SAMN04487996_12822 | Phosphoribosylanthranilate isomerase. | Para-aminobenzoate synthetase component 1. | 0.930 |
SDE22133.1 | SDH51272.1 | SAMN04487996_10487 | SAMN04487996_1422 | Phosphoribosylanthranilate isomerase. | Anthranilate synthase component 1. | 0.930 |
SDE22133.1 | SDH51326.1 | SAMN04487996_10487 | SAMN04487996_1423 | Phosphoribosylanthranilate isomerase. | Anthranilate synthase component 2. | 0.960 |
SDE22133.1 | SDH51429.1 | SAMN04487996_10487 | SAMN04487996_1425 | Phosphoribosylanthranilate isomerase. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.985 |
SDE22133.1 | ilvA | SAMN04487996_10487 | SAMN04487996_106117 | Phosphoribosylanthranilate isomerase. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.517 |
SDE22133.1 | trpA | SAMN04487996_10487 | SAMN04487996_14210 | Phosphoribosylanthranilate isomerase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.961 |
SDE22133.1 | trpB | SAMN04487996_10487 | SAMN04487996_1427 | Phosphoribosylanthranilate isomerase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.961 |
SDE22133.1 | trpD | SAMN04487996_10487 | SAMN04487996_1424 | Phosphoribosylanthranilate isomerase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.985 |
SDG12296.1 | SDE22133.1 | SAMN04487996_115107 | SAMN04487996_10487 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Phosphoribosylanthranilate isomerase. | 0.767 |
SDG12296.1 | SDH51429.1 | SAMN04487996_115107 | SAMN04487996_1425 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.633 |
SDG12296.1 | ilvA | SAMN04487996_115107 | SAMN04487996_106117 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.870 |
SDG12296.1 | trpA | SAMN04487996_115107 | SAMN04487996_14210 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.865 |
SDG12296.1 | trpB | SAMN04487996_115107 | SAMN04487996_1427 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.930 |
SDG12296.1 | trpF | SAMN04487996_115107 | SAMN04487996_1426 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.723 |
SDH07697.1 | SDE22133.1 | SAMN04487996_12822 | SAMN04487996_10487 | Para-aminobenzoate synthetase component 1. | Phosphoribosylanthranilate isomerase. | 0.930 |
SDH07697.1 | SDH51272.1 | SAMN04487996_12822 | SAMN04487996_1422 | Para-aminobenzoate synthetase component 1. | Anthranilate synthase component 1. | 0.887 |
SDH07697.1 | SDH51326.1 | SAMN04487996_12822 | SAMN04487996_1423 | Para-aminobenzoate synthetase component 1. | Anthranilate synthase component 2. | 0.999 |
SDH07697.1 | SDH51429.1 | SAMN04487996_12822 | SAMN04487996_1425 | Para-aminobenzoate synthetase component 1. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.999 |
SDH07697.1 | trpA | SAMN04487996_12822 | SAMN04487996_14210 | Para-aminobenzoate synthetase component 1. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.947 |