node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C7YMM2_NECH7 | C7YNQ3_NECH7 | C7YMM2 | C7YNQ3 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.756 |
C7YMM2_NECH7 | C7YPC2_NECH7 | C7YMM2 | C7YPC2 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | DUF1767 domain-containing protein. | 0.748 |
C7YMM2_NECH7 | C7YQ21_NECH7 | C7YMM2 | C7YQ21 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | Predicted protein. | 0.929 |
C7YMM2_NECH7 | C7YRU9_NECH7 | C7YMM2 | C7YRU9 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.980 |
C7YMM2_NECH7 | C7YVU1_NECH7 | C7YMM2 | C7YVU1 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family. | 0.965 |
C7YMM2_NECH7 | C7YZQ1_NECH7 | C7YMM2 | C7YZQ1 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | DEAD domain-containing protein. | 0.570 |
C7YMM2_NECH7 | C7Z584_NECH7 | C7YMM2 | C7Z584 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | Uncharacterized protein. | 0.872 |
C7YMM2_NECH7 | C7Z7E5_NECH7 | C7YMM2 | C7Z7E5 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | Uncharacterized protein. | 0.852 |
C7YMM2_NECH7 | C7Z7F6_NECH7 | C7YMM2 | C7Z7F6 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | Predicted protein. | 0.512 |
C7YMM2_NECH7 | C7ZPJ4_NECH7 | C7YMM2 | C7ZPJ4 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | Uncharacterized protein. | 0.667 |
C7YNQ3_NECH7 | C7YMM2_NECH7 | C7YNQ3 | C7YMM2 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | 0.756 |
C7YNQ3_NECH7 | C7YPC2_NECH7 | C7YNQ3 | C7YPC2 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DUF1767 domain-containing protein. | 0.969 |
C7YNQ3_NECH7 | C7YQ21_NECH7 | C7YNQ3 | C7YQ21 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Predicted protein. | 0.877 |
C7YNQ3_NECH7 | C7YRU9_NECH7 | C7YNQ3 | C7YRU9 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.988 |
C7YNQ3_NECH7 | C7YVU1_NECH7 | C7YNQ3 | C7YVU1 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family. | 0.781 |
C7YNQ3_NECH7 | C7YZQ1_NECH7 | C7YNQ3 | C7YZQ1 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DEAD domain-containing protein. | 0.523 |
C7YNQ3_NECH7 | C7Z584_NECH7 | C7YNQ3 | C7Z584 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Uncharacterized protein. | 0.868 |
C7YNQ3_NECH7 | C7Z7E5_NECH7 | C7YNQ3 | C7Z7E5 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Uncharacterized protein. | 0.804 |
C7YNQ3_NECH7 | C7Z7F6_NECH7 | C7YNQ3 | C7Z7F6 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Predicted protein. | 0.698 |
C7YPC2_NECH7 | C7YMM2_NECH7 | C7YPC2 | C7YMM2 | DUF1767 domain-containing protein. | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | 0.748 |