Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFK05851.1Uncharacterized Fe-S center protein; PFAM: Domain of unknown function (DUF362). (356 aa)    
Predicted Functional Partners:
AFK06170.1
Hydrogenase, Fe-only; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron hydrogenase small subunit; TIGRFAM: [FeFe] hydrogenase, group A.
  
 
 0.937
AFK06475.1
Hypothetical protein; PFAM: Domain of unknown function (DUF362).
 
    0.629
AFK06188.1
PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit.
  
 
 0.561
AFK06191.1
PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit.
  
 
 0.561
AFK07793.1
Hypothetical protein.
  
 
 0.522
AFK07630.1
PFAM: Domain of unknown function (DUF1848).
  
     0.521
AFK06706.1
Hypothetical protein; PFAM: Pyruvate kinase, alpha/beta domain.
  
   
 0.422
AFK05852.1
PFAM: HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Hpt domain.
       0.410
Your Current Organism:
Mesotoga prima
NCBI taxonomy Id: 660470
Other names: M. prima MesG1.Ag.4.2, Mesotoga prima MesG1.Ag.4.2, Thermotogales bacterium MesG1.Ag.4.2
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