Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFK06369.1Hypothetical protein. (212 aa)    
Predicted Functional Partners:
comB
Phosphosulfolactate phosphohydrolase-like enzyme; PFAM: 2-phosphosulpholactate phosphatase; TIGRFAM: 2-phosphosulfolactate phosphatase; Belongs to the ComB family.
 
     0.770
AFK06366.1
Fructose-2,6-bisphosphatase; PFAM: Phosphoglycerate mutase family.
       0.727
AFK06361.1
Radical SAM-linked protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2344); TIGRFAM: radical SAM-linked protein.
 
     0.726
AFK06368.1
Hypothetical protein.
       0.714
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
       0.695
AFK06364.1
Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
       0.695
AFK06365.1
PFAM: Bacterial DNA polymerase III alpha subunit.
       0.695
AFK07379.1
Glycogen debranching enzyme.
  
     0.670
AFK07308.1
Glycogen debranching enzyme.
  
     0.666
AFK06370.1
PFAM: Aminotransferase class I and II.
       0.647
Your Current Organism:
Mesotoga prima
NCBI taxonomy Id: 660470
Other names: M. prima MesG1.Ag.4.2, Mesotoga prima MesG1.Ag.4.2, Thermotogales bacterium MesG1.Ag.4.2
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