Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFK06486.1TIGR02453 family protein; PFAM: Conserved hypothetical protein (DUF2461); TIGRFAM: TIGR02453 family protein. (230 aa)    
Predicted Functional Partners:
AFK06485.1
PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase, HisJ family; Belongs to the PHP hydrolase family. HisK subfamily.
       0.774
AFK06484.1
Site-specific recombinase XerD; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; Belongs to the 'phage' integrase family.
 
     0.719
Your Current Organism:
Mesotoga prima
NCBI taxonomy Id: 660470
Other names: M. prima MesG1.Ag.4.2, Mesotoga prima MesG1.Ag.4.2, Thermotogales bacterium MesG1.Ag.4.2
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