Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFK06616.1PFAM: Phenylalanine and histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase. (494 aa)    
Predicted Functional Partners:
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.998
hutI
Imidazolonepropionase; PFAM: Amidohydrolase family; TIGRFAM: imidazolonepropionase.
 
  
 0.928
AFK06898.1
Amidohydrolase, imidazolonepropionase; PFAM: Amidohydrolase family.
  
  
 0.698
AFK06618.1
ABC-type polar amino acid transport system, ATPase component; PFAM: ABC transporter.
       0.613
AFK06619.1
PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family.
       0.613
AFK06617.1
PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family.
       0.604
AFK06700.1
PFAM: beta-N-acetylglucosaminidase.
   
    0.509
AFK06620.1
Periplasmic component of amino acid ABC-type transporter/signal transduction system; PFAM: Bacterial extracellular solute-binding proteins, family 3.
     
 0.495
AFK06291.1
Methenyl tetrahydrofolate cyclohydrolase; PFAM: Formiminotransferase-cyclodeaminase.
  
  
 0.490
AFK06615.1
GMP synthase family protein; PFAM: Glutamine amidotransferase class-I.
       0.428
Your Current Organism:
Mesotoga prima
NCBI taxonomy Id: 660470
Other names: M. prima MesG1.Ag.4.2, Mesotoga prima MesG1.Ag.4.2, Thermotogales bacterium MesG1.Ag.4.2
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