Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFK06665.1PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. (319 aa)    
Predicted Functional Partners:
AFK06664.1
PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like domain protein.
  
 0.983
AFK06042.1
Selenocysteine lyase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufSfamily.
  
 
  0.908
AFK06964.1
Cystathionine beta-lyase/cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: methionine gamma-lyase.
  
 
 0.906
AFK06662.1
Membrane protease subunit, stomatin/prohibitin; PFAM: SPFH domain / Band 7 family.
  
  
 0.677
AFK06661.1
Membrane protein implicated in regulation of membrane protease activity; PFAM: NfeD-like.
       0.619
AFK07637.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.600
AFK05899.1
Thioredoxin domain-containing protein; PFAM: Thioredoxin.
  
 
 0.589
AFK06663.1
Hypothetical protein.
       0.583
rplI
Ribosomal protein L9; Binds to the 23S rRNA.
  
    0.576
AFK06660.1
Metal-dependent hydrolase, beta-lactamase superfamily III; TIGRFAM: ribonuclease Z, Thermotoga type.
  
    0.576
Your Current Organism:
Mesotoga prima
NCBI taxonomy Id: 660470
Other names: M. prima MesG1.Ag.4.2, Mesotoga prima MesG1.Ag.4.2, Thermotogales bacterium MesG1.Ag.4.2
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