Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFK06774.1PFAM: Phosphorylase superfamily. (221 aa)    
Predicted Functional Partners:
AFK05787.1
Cytosine deaminase-like metal-dependent hydrolase.
    
 0.913
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
    
 0.904
AFK06778.1
ABC-type cobalt transport system, ATPase component; PFAM: ABC transporter.
     
 0.812
AFK06776.1
16S RNA G1207 methylase RsmC; PFAM: Methyltransferase small domain.
       0.789
AFK06779.1
Uncharacterized membrane protein, possible Na+ channel or pump; PFAM: Protein of unknown function (DUF554).
       0.789
AFK06775.1
HIT family hydrolase, diadenosine tetraphosphate hydrolase; PFAM: HIT domain.
       0.788
AFK06777.1
ABC-type cobalt transport system, ATPase component; PFAM: ABC transporter.
     
 0.778
AFK06773.1
PFAM: Protein of unknown function (DUF1292).
       0.645
metG
Protein containing C-terminal region/beta chain of methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.471
AFK06443.1
Cysteine desulfurase family protein; PFAM: Aminotransferase class-V.
 
  
 0.461
Your Current Organism:
Mesotoga prima
NCBI taxonomy Id: 660470
Other names: M. prima MesG1.Ag.4.2, Mesotoga prima MesG1.Ag.4.2, Thermotogales bacterium MesG1.Ag.4.2
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