STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFK07042.1DMT(drug/metabolite transporter) superfamily permease; PFAM: EamA-like transporter family. (293 aa)    
Predicted Functional Partners:
AFK07044.1
PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
    0.793
AFK07045.1
Putative protein-S-isoprenylcysteine methyltransferase; PFAM: Acyltransferase.
  
  
 0.789
AFK07043.1
PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
       0.787
AFK07041.1
PEGA domain-containing protein; PFAM: PEGA domain.
 
     0.730
AFK07036.1
PFAM: Putative Fe-S cluster; TIGRFAM: electron transport complex, RnfABCDGE type, B subunit.
  
    0.681
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
  
    0.679
ispG
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
       0.679
AFK07038.1
Putative membrane-associated Zn-dependent protease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP.
       0.670
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
       0.670
rnfA
Electron transport complex, RnfABCDGE type, A subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
  
    0.665
Your Current Organism:
Mesotoga prima
NCBI taxonomy Id: 660470
Other names: M. prima MesG1.Ag.4.2, Mesotoga prima MesG1.Ag.4.2, Thermotogales bacterium MesG1.Ag.4.2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.