Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFK07624.1PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E. (219 aa)    
Predicted Functional Partners:
AFK07623.1
Putative phosphatase; PFAM: haloacid dehalogenase-like hydrolase.
 
    
0.789
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
  
  
 0.650
AFK05875.1
Putative phosphoesterase or phosphohydrolase.
 
     0.538
pgk
Phosphoglycerate kinase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
  
 0.416
AFK07599.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; PFAM: Domain of unknown function; domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family; pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric.
     
 0.406
AFK07626.1
PFAM: Papain family cysteine protease.
       0.402
Your Current Organism:
Mesotoga prima
NCBI taxonomy Id: 660470
Other names: M. prima MesG1.Ag.4.2, Mesotoga prima MesG1.Ag.4.2, Thermotogales bacterium MesG1.Ag.4.2
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.