Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFK07637.1Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (213 aa)    
Predicted Functional Partners:
AFK06664.1
PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like domain protein.
  
  
 0.833
AFK07112.1
PFAM: NHL repeat; Redoxin.
  
 0.772
pgk
Phosphoglycerate kinase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.747
AFK07577.1
TIGRFAM: small redox-active disulfide protein 2.
  
 0.727
hflX
GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
      0.667
AFK07792.1
Thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; BFD-like [2Fe-2S] binding domain; 4Fe-4S binding domain.
  
 
 0.662
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.656
AFK06326.1
Putative redox protein, regulator of disulfide bond formation; PFAM: SirA-like protein; Belongs to the sulfur carrier protein TusA family.
  
  
 0.645
AFK06724.1
Ferritin-like protein; Iron-storage protein.
  
  
 0.618
AFK05826.1
PFAM: Catalase; Catalase-related immune-responsive; Belongs to the catalase family.
  
 
 0.614
Your Current Organism:
Mesotoga prima
NCBI taxonomy Id: 660470
Other names: M. prima MesG1.Ag.4.2, Mesotoga prima MesG1.Ag.4.2, Thermotogales bacterium MesG1.Ag.4.2
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