Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFK07792.1Thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; BFD-like [2Fe-2S] binding domain; 4Fe-4S binding domain. (605 aa)    
Predicted Functional Partners:
AFK07793.1
Hypothetical protein.
   
 0.996
AFK07599.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; PFAM: Domain of unknown function; domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family; pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric.
  
 
 0.968
AFK07791.1
glycine/D-amino acid oxidase, deaminating; PFAM: FAD dependent oxidoreductase; TIGRFAM: sarcosine oxidase, beta subunit family, heterotetrameric form.
  
 0.965
AFK06781.1
2-oxoacid:acceptor oxidoreductase, alpha subunit; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit.
  
 
 0.951
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
 
  
 0.909
AFK07790.1
PFAM: Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 2, putative.
  
  
 0.897
AFK06178.1
Putative dehydrogenase; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase.
 
  
 0.721
AFK05899.1
Thioredoxin domain-containing protein; PFAM: Thioredoxin.
  
 
 0.679
AFK07637.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.662
AFK07112.1
PFAM: NHL repeat; Redoxin.
  
 
 0.655
Your Current Organism:
Mesotoga prima
NCBI taxonomy Id: 660470
Other names: M. prima MesG1.Ag.4.2, Mesotoga prima MesG1.Ag.4.2, Thermotogales bacterium MesG1.Ag.4.2
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