Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFK07811.1PFAM: Response regulator receiver domain; Stage II sporulation protein E (SpoIIE). (368 aa)    
Predicted Functional Partners:
AFK05852.1
PFAM: HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Hpt domain.
 
  
 0.946
AFK07812.1
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor.
 
 
 0.940
AFK07894.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain.
 
  
 0.924
AFK07813.1
Anti-sigma regulatory factor (Ser/Thr protein kinase); PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.916
AFK07893.1
PFAM: Bacterial extracellular solute-binding proteins, family 3.
  
  
 0.822
AFK06566.1
PAS domain S-box; PFAM: 5TMR of 5TMR-LYT; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.
 
  
 0.794
AFK07810.1
ABC-type transport system, involved in lipoprotein release, permease component; PFAM: Predicted permease.
 
     0.749
AFK08244.1
PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
  
 0.745
AFK06252.1
Putative transcriptional regulator, contains C-terminal CBS domains; PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 
 0.732
AFK05837.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
  
 0.728
Your Current Organism:
Mesotoga prima
NCBI taxonomy Id: 660470
Other names: M. prima MesG1.Ag.4.2, Mesotoga prima MesG1.Ag.4.2, Thermotogales bacterium MesG1.Ag.4.2
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