Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AFK07907.1Diguanylate cyclase; PFAM: HD domain; HAMP domain; Cache domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; uncharacterized domain HDIG; diguanylate cyclase (GGDEF) domain. (902 aa)    
Predicted Functional Partners:
AFK07895.1
PAS domain S-box; PFAM: EAL domain; GGDEF domain; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box.
 
 
 0.957
AFK07894.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain.
 
 
 0.941
AFK05852.1
PFAM: HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Hpt domain.
 
 
 0.862
AFK07893.1
PFAM: Bacterial extracellular solute-binding proteins, family 3.
 
 
 0.860
AFK06339.1
PFAM: GGDEF domain; GAF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain.
 
 
0.827
AFK06567.1
Putative domain HDIG-containing protein; PFAM: HD domain; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box; uncharacterized domain HDIG.
 
 
0.750
AFK07972.1
PFAM: HD domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain.
 
 
0.746
AFK07978.1
PFAM: HD domain; GAF domain; PAS fold; TIGRFAM: PAS domain S-box.
 
 
0.738
AFK07501.1
Putative domain HDIG-containing protein; PFAM: HD domain; GAF domain; PAS fold; TIGRFAM: PAS domain S-box; uncharacterized domain HDIG.
 
 
0.735
AFK07434.1
Hypothetical protein.
 
 
 0.710
Your Current Organism:
Mesotoga prima
NCBI taxonomy Id: 660470
Other names: M. prima MesG1.Ag.4.2, Mesotoga prima MesG1.Ag.4.2, Thermotogales bacterium MesG1.Ag.4.2
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