STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDY33524.1Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. (334 aa)    
Predicted Functional Partners:
SDX78979.1
Intein C-terminal splicing region/intein N-terminal splicing region.
   
 0.890
priL
DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
   
 
 0.680
SDY35263.1
DNA polymerase I.
  
 0.593
SDY15718.1
DNA polymerase I.
  
 0.591
SDX55269.1
DNA polymerase I.
  
 0.543
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
   
 
 0.526
SDY13357.1
Hypothetical protein.
   
 
 0.526
SDY32005.1
Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication.
  
   
 0.518
SDY54009.1
Hypothetical protein.
  
     0.516
SDY01138.1
Hypothetical protein.
  
     0.509
Your Current Organism:
Halobellus clavatus
NCBI taxonomy Id: 660517
Other names: CGMCC 1.10118, H. clavatus, Halobacteriaceae archaeon TBN12, Halobacteriaceae archaeon TNN18, Halobellus clavatus Cui et al. 2011, JCM 16424, strain TNN18
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.