STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDF05072.1Isocitrate dehydrogenase (NADP). (420 aa)    
Predicted Functional Partners:
SDE87859.1
Citrate synthase.
 
 
 0.994
SDG01627.1
Aconitase.
 
 0.994
SDF26988.1
Malate dehydrogenase (NAD); Belongs to the LDH/MDH superfamily.
  
 
 0.984
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.973
SDE81552.1
3-isopropylmalate dehydrogenase.
 
0.953
SDE94945.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
  
 
 0.942
SDF86537.1
NADH-quinone oxidoreductase subunit I.
   
 
 0.935
SDE78219.1
Glutamate dehydrogenase (NADP); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.917
SDF86585.1
NADH-quinone oxidoreductase subunit C/D.
  
  
 0.915
fumC
Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.886
Your Current Organism:
Halorientalis regularis
NCBI taxonomy Id: 660518
Other names: CGMCC 1.10123, H. regularis, Halobacteriaceae archaeon TBN19, Halobacteriaceae archaeon TNN28, Halorientalis regularis Cui et al. 2011, JCM 16425, strain TNN28
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.