STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDN13735.1Thioredoxin. (139 aa)    
Predicted Functional Partners:
msrA
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.811
SDL88312.1
Dihydrolipoamide dehydrogenase.
   
 0.636
SDM00638.1
Dihydrolipoamide dehydrogenase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
   
 0.636
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.616
SDM17192.1
Hypothetical protein.
    
 0.563
SDM21257.1
Thioredoxin reductase (NADPH).
 
 
 0.555
rpl5
Large subunit ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
  
   0.502
SDM52127.1
Peptide-methionine (R)-S-oxide reductase.
   
 0.493
SDM56652.1
Peptidyl-prolyl cis-trans isomerase A (cyclophilin A).
  
 0.492
SDM19185.1
Cytochrome c oxidase subunit 2.
    
 
 0.478
Your Current Organism:
Halogranum gelatinilyticum
NCBI taxonomy Id: 660521
Other names: CGMCC 1.10119, H. gelatinilyticum, Halobacteriaceae archaeon TNN44, Halogranum gelatinilyticum Cui et al. 2011, JCM 16426, strain TNN44
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