Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
btuBTonB-dependent vitamin B12 receptor; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. (628 aa)    
Predicted Functional Partners:
DSJ_14625
TonB system transport protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 
 0.912
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
     
 0.834
ompA
Porin OmpA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
  
 0.623
lamB
Maltoporin; Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family.
  
  
 0.601
ompC
Porin OmpC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Gram-negative porin family.
    
 0.562
phoE
Porin OmpC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Gram-negative porin family.
    
 0.562
DSJ_11315
Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.555
btuF
Vitamin B12 ABC transporter substrate-binding protein BtuF; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
 
   
 0.548
wzzE
Polysaccharide chain length modulation protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family.
  
     0.481
flgK
Flagellar hook-associated protein FlgK; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.459
Your Current Organism:
Pantoea stewartii
NCBI taxonomy Id: 660596
Other names: P. stewartii subsp. stewartii DC283, Pantoea stewartii subsp. stewartii DC283, Pantoea stewartii subsp. stewartii str. DC283, Pantoea stewartii subsp. stewartii strain DC283
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