Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rseCSoxR reducing system protein RseC; Involved in the reduction of the SoxR iron-sulfur cluster; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)    
Predicted Functional Partners:
rseB
sigma-E factor regulatory protein RseB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.996
rseA
Anti-sigma factor; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading [...]
 
  
 0.938
rpoE
RNA polymerase sigma factor RpoE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.811
yrfF
Intracellular growth attenuator protein igaA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.763
DSJ_21735
TIGR02099 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.736
nlpI
Lipoprotein NlpI; May be involved in cell division.
  
     0.653
rraB
Ribonuclease E inhibitor B; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.603
ompX
Outer membrane protein OmpX; OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.601
lepB
S26 family signal peptidase; Catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
       0.587
holE
DNA polymerase III subunit theta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.544
Your Current Organism:
Pantoea stewartii
NCBI taxonomy Id: 660596
Other names: P. stewartii subsp. stewartii DC283, Pantoea stewartii subsp. stewartii DC283, Pantoea stewartii subsp. stewartii str. DC283, Pantoea stewartii subsp. stewartii strain DC283
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.