| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DSJ_08630 | dusC | DSJ_08630 | DSJ_08640 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA dihydrouridine(16) synthase DusC; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | 0.432 |
| DSJ_08630 | rhlE | DSJ_08630 | DSJ_08635 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. | 0.432 |
| dusC | DSJ_08630 | DSJ_08640 | DSJ_08630 | tRNA dihydrouridine(16) synthase DusC; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.432 |
| dusC | fis | DSJ_08640 | DSJ_21815 | tRNA dihydrouridine(16) synthase DusC; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | Fis family transcriptional regulator; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | 0.637 |
| dusC | guaA | DSJ_08640 | DSJ_07590 | tRNA dihydrouridine(16) synthase DusC; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.451 |
| dusC | guaB | DSJ_08640 | DSJ_07585 | tRNA dihydrouridine(16) synthase DusC; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.408 |
| dusC | rhlE | DSJ_08640 | DSJ_08635 | tRNA dihydrouridine(16) synthase DusC; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | ATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. | 0.795 |
| dusC | trmA | DSJ_08640 | DSJ_02805 | tRNA dihydrouridine(16) synthase DusC; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | tRNA (uridine(54)-C5)-methyltransferase TrmA; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). | 0.413 |
| dusC | truA | DSJ_08640 | DSJ_17240 | tRNA dihydrouridine(16) synthase DusC; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | tRNA pseudouridine(38-40) synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.433 |
| dusC | truB | DSJ_08640 | DSJ_04080 | tRNA dihydrouridine(16) synthase DusC; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | tRNA pseudouridine(55) synthase TruB; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.412 |
| fis | dusC | DSJ_21815 | DSJ_08640 | Fis family transcriptional regulator; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | tRNA dihydrouridine(16) synthase DusC; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | 0.637 |
| guaA | dusC | DSJ_07590 | DSJ_08640 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | tRNA dihydrouridine(16) synthase DusC; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | 0.451 |
| guaA | guaB | DSJ_07590 | DSJ_07585 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA | truA | DSJ_07590 | DSJ_17240 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | tRNA pseudouridine(38-40) synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.419 |
| guaA | truB | DSJ_07590 | DSJ_04080 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | tRNA pseudouridine(55) synthase TruB; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.946 |
| guaB | dusC | DSJ_07585 | DSJ_08640 | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | tRNA dihydrouridine(16) synthase DusC; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | 0.408 |
| guaB | guaA | DSJ_07585 | DSJ_07590 | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
| guaB | truA | DSJ_07585 | DSJ_17240 | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | tRNA pseudouridine(38-40) synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.489 |
| guaB | truB | DSJ_07585 | DSJ_04080 | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | tRNA pseudouridine(55) synthase TruB; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.574 |
| rhlE | DSJ_08630 | DSJ_08635 | DSJ_08630 | ATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.432 |