node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
kdsA | kdsD | DSJ_12595 | DSJ_03940 | 3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. | D-arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.989 |
kdsA | lpxA | DSJ_12595 | DSJ_06700 | 3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.844 |
kdsA | lpxB | DSJ_12595 | DSJ_06705 | 3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.847 |
kdsA | lpxC | DSJ_12595 | DSJ_06275 | 3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.844 |
kdsA | lpxD | DSJ_12595 | DSJ_06690 | 3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. | UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.834 |
kdsA | lpxK | DSJ_12595 | DSJ_09570 | 3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.849 |
kdsA | lpxL | DSJ_12595 | DSJ_10460 | 3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. | Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). | 0.493 |
kdsA | waaA | DSJ_12595 | DSJ_02460 | 3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.844 |
kdsD | kdsA | DSJ_03940 | DSJ_12595 | D-arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. | 0.989 |
kdsD | lpxA | DSJ_03940 | DSJ_06700 | D-arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.877 |
kdsD | lpxB | DSJ_03940 | DSJ_06705 | D-arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.880 |
kdsD | lpxC | DSJ_03940 | DSJ_06275 | D-arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.882 |
kdsD | lpxD | DSJ_03940 | DSJ_06690 | D-arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.870 |
kdsD | lpxK | DSJ_03940 | DSJ_09570 | D-arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.889 |
kdsD | lpxL | DSJ_03940 | DSJ_10460 | D-arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). | 0.669 |
kdsD | lpxM | DSJ_03940 | DSJ_15250 | D-arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. | 0.585 |
kdsD | waaA | DSJ_03940 | DSJ_02460 | D-arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.879 |
lolA | lpxL | DSJ_09480 | DSJ_10460 | Outer-membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). | 0.494 |
lolA | lpxM | DSJ_09480 | DSJ_15250 | Outer-membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. | 0.607 |
lpxA | kdsA | DSJ_06700 | DSJ_12595 | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. | 0.844 |