STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sufSBifunctional cysteine desulfurase/selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. (407 aa)    
Predicted Functional Partners:
sufC
Fe-S cluster assembly ATPase SufC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.988
sufD
FeS cluster assembly protein SufD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.984
sufB
Fe-S cluster assembly protein SufB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.977
sufE
Cysteine desufuration protein SufE; Acts with SufS to catalyze the formation of L-alanine from L-cysteine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.952
trxB
Thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.915
metB
Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.900
DSJ_05015
Cysteine desulfurase, sulfur acceptor subunit CsdE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.844
sufA
Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family.
  
 
 0.758
ybhP
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.677
dadX
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
 
 0.534
Your Current Organism:
Pantoea stewartii
NCBI taxonomy Id: 660596
Other names: P. stewartii subsp. stewartii DC283, Pantoea stewartii subsp. stewartii DC283, Pantoea stewartii subsp. stewartii str. DC283, Pantoea stewartii subsp. stewartii strain DC283
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.