| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cvpA | dedD | DSJ_17215 | DSJ_17220 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein DedD; Non-essential cell division protein that could be required for efficient cell constriction. | 0.586 |
| cvpA | djlA | DSJ_17215 | DSJ_06095 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | 0.569 |
| cvpA | ftsQ | DSJ_17215 | DSJ_06260 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.534 |
| cvpA | metJ | DSJ_17215 | DSJ_02725 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.569 |
| cvpA | purC | DSJ_17215 | DSJ_07685 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. | 0.778 |
| cvpA | purE | DSJ_17215 | DSJ_18700 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.754 |
| cvpA | purF | DSJ_17215 | DSJ_17210 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.965 |
| cvpA | purL | DSJ_17215 | DSJ_07400 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.981 |
| cvpA | purM | DSJ_17215 | DSJ_07800 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.768 |
| cvpA | zapA | DSJ_17215 | DSJ_04760 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Z-ring-associated protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | 0.554 |
| dedD | cvpA | DSJ_17220 | DSJ_17215 | Cell division protein DedD; Non-essential cell division protein that could be required for efficient cell constriction. | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.586 |
| dedD | ftsQ | DSJ_17220 | DSJ_06260 | Cell division protein DedD; Non-essential cell division protein that could be required for efficient cell constriction. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.490 |
| dedD | metJ | DSJ_17220 | DSJ_02725 | Cell division protein DedD; Non-essential cell division protein that could be required for efficient cell constriction. | Transcriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.589 |
| dedD | purF | DSJ_17220 | DSJ_17210 | Cell division protein DedD; Non-essential cell division protein that could be required for efficient cell constriction. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.513 |
| djlA | cvpA | DSJ_06095 | DSJ_17215 | Molecular chaperone DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.569 |
| ftsQ | cvpA | DSJ_06260 | DSJ_17215 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.534 |
| ftsQ | dedD | DSJ_06260 | DSJ_17220 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Cell division protein DedD; Non-essential cell division protein that could be required for efficient cell constriction. | 0.490 |
| ftsQ | zapA | DSJ_06260 | DSJ_04760 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Z-ring-associated protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | 0.509 |
| metJ | cvpA | DSJ_02725 | DSJ_17215 | Transcriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.569 |
| metJ | dedD | DSJ_02725 | DSJ_17220 | Transcriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Cell division protein DedD; Non-essential cell division protein that could be required for efficient cell constriction. | 0.589 |