STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfcLHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)    
Predicted Functional Partners:
seqA
Replication initiation regulator SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
     0.766
yejL
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0352 family.
  
     0.761
yheV
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.747
yciU
Highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0263 family.
  
     0.747
ycbW
Cell division protein ZapC; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
  
     0.744
bamC
Outer membrane protein assembly factor BamC; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.736
fadR
Fatty acid metabolism regulator; Multifunctional regulator of fatty acid metabolism.
  
     0.728
dedD
Cell division protein DedD; Non-essential cell division protein that could be required for efficient cell constriction.
  
     0.719
yfcM
Elongation factor P hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.713
syd
SecY-interacting protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.
  
     0.701
Your Current Organism:
Pantoea stewartii
NCBI taxonomy Id: 660596
Other names: P. stewartii subsp. stewartii DC283, Pantoea stewartii subsp. stewartii DC283, Pantoea stewartii subsp. stewartii str. DC283, Pantoea stewartii subsp. stewartii strain DC283
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.