Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DSJ_17895Helicase DnaB; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
 0.929
DSJ_12090
DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.926
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
  
  
 
0.912
dnaA
Chromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 0.829
dnaC
DNA replication protein DnaC; Acts to load the DnaB helicase onto the initiation site during DNA replication; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.819
DSJ_17900
DNA replication protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.818
DSJ_17890
Nucleoside 2-deoxyribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.773
DSJ_10935
DNA replication protein DnaC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.728
dnaE
DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.665
holB
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.605
Your Current Organism:
Pantoea stewartii
NCBI taxonomy Id: 660596
Other names: P. stewartii subsp. stewartii DC283, Pantoea stewartii subsp. stewartii DC283, Pantoea stewartii subsp. stewartii str. DC283, Pantoea stewartii subsp. stewartii strain DC283
Server load: low (16%) [HD]