STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argRArginine repressor, putative; Regulates arginine biosynthesis genes. (151 aa)    
Predicted Functional Partners:
argB
Acetylglutamate kinase.
  
  
 0.895
ACN95093.1
Amino acid ABC transporter, periplasmic amino acid binding protein; Belongs to the bacterial solute-binding protein 3 family.
 
   
 0.721
ACN95094.1
Amino acid ABC transporter, permease.
 
   
 0.713
ACN95095.1
Amino acid ABC transporter, ATP-binding protein.
 
   
 0.705
argD
Acetylornithine aminotransferase.
  
  
 0.614
ACN95986.1
Ornithine/acetylornithine aminotransferase.
  
  
 0.614
pheT
Phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.557
guaB
Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.494
argS
arginyl-tRNA synthetase.
  
  
 0.470
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
  
 0.447
Your Current Organism:
Wolbachia sp. wRi
NCBI taxonomy Id: 66084
Other names: W. sp. wRi, Wolbachia endosymbiont Drosophila simulans strain Riverside
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.