Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LLO_0804Equals llo0804; similar to inorganic transporter and to carbonic anhydrase (bi-functional). (769 aa)    
Predicted Functional Partners:
proS
Prolyl-tRNA synthetase (Proline--tRNA ligase)(ProRS)(Global RNA synthesis factor); Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other act [...]
  
    0.678
ydaO
Putative C32 tRNA thiolase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
  
    0.666
LLO_3045
Hypothetical protein; Equals llo3045.
 
     0.624
LLO_0722
Putative polyketide synthase of type I; Equals llo0722.
 
 
 0.618
pcm
protein-L-isoaspartate-O-methyltransferase; Equals llo0807; similar to L-isoaspartate carboxylmethyltransferase protein pcm.
       0.591
LLO_2626
Equals llo2626; similar to conserved hypothetical protein.
   
 
 0.581
tolC
Equals llo0806; similar to outer membrane protein TolC.
       0.580
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
   
 0.549
LLO_2124
Equals llo2124; similar to RND efflux membrane fusion proteins.
  
     0.519
LLO_2123
Putative outer membrane component of multidrug efflux pump; Equals llo2123.
  
     0.516
Your Current Organism:
Legionella longbeachae
NCBI taxonomy Id: 661367
Other names: L. longbeachae NSW150, Legionella longbeachae NSW150, Legionella longbeachae str. NSW150, Legionella longbeachae strain NSW150
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