Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tdhThreonine dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (340 aa)    
Predicted Functional Partners:
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
 
 
 0.993
ydfG
L-allo-threonine dehydrogenase, NAD(P)-binding; Equals llo0454; similar to oxidoreductase, short chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.903
LLO_0811
Equals llo0811; similar to enhanced entry protein EnhA.
       0.707
yjjK
Putative fused transporter subunits of ABC superfamily: ATP-binding components; Equals llo0810; similar to ABC transporter, ATP-binding protein.
       0.652
bioF
8-amino-7-oxononanoate synthase; Equals llo1731.
 
  
 0.497
LLO_0978
Putative luciferase-like monooxygenase; Equals llo0978.
     
 0.491
LLO_3178
Putative aminotransferase; Equals llo3178.
 
  
 0.473
pcm
protein-L-isoaspartate-O-methyltransferase; Equals llo0807; similar to L-isoaspartate carboxylmethyltransferase protein pcm.
  
    0.466
ydaO
Putative C32 tRNA thiolase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
       0.454
tolC
Equals llo0806; similar to outer membrane protein TolC.
       0.454
Your Current Organism:
Legionella longbeachae
NCBI taxonomy Id: 661367
Other names: L. longbeachae NSW150, Legionella longbeachae NSW150, Legionella longbeachae str. NSW150, Legionella longbeachae strain NSW150
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